Reversible inactivation of macaque frontal eye field

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Acute activation and inactivation of macaque frontal eye field with GABA-related drugs.

1. This project tests the behavioral effects of reversible activation and inactivation of sites within the frontal eye field of rhesus monkeys with microinjections of the gamma-aminobutyric acid (GABA)-related drugs bicuculline and muscimol. 2. Muscimol injections impaired the monkeys' ability to make both visually and memory-guided saccades to targets at the center of the area represented by t...

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Bilateral saccadic deficits following large and reversible inactivation of unilateral frontal eye 1 field

Correspondence should be addressed to: 9 10 Dr. Brian D. Corneil 11 Robarts Research Institute 12 100 Perth Drive 13 London, Ontario, Canada N6A 5K8 14 Phone: (519) 663-5777, ext 24132 15 E-mail: [email protected] 16 17 Number of figures: 14 Number of Tables: 0 18 Number of pages: 48 19 Words in abstract: 232 20 21

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Bilateral saccadic deficits following large and reversible inactivation of unilateral frontal eye field.

Inactivation permits direct assessment of the functional contribution of a given brain area to behavior. Previous inactivation studies of the frontal eye field (FEF) have either used large permanent ablations or reversible pharmacological techniques that only inactivate a small volume of tissue. Here we evaluated the impact of large, yet reversible, FEF inactivation on visually guided, delayed,...

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Radial motion bias in macaque frontal eye field.

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ژورنال

عنوان ژورنال: Experimental Brain Research

سال: 1997

ISSN: 0014-4819

DOI: 10.1007/pl00005752